Chemical formula: C₃₅H₃₈Cl₂N₈O₄ Molecular mass: 705.633 g/mol PubChem compound: 55283
Itraconazole is indicated for:
Population group: only adults (18 years old or older)
For the treatment of oral and/or oesophageal candidosis in HIV-positive or other immunocompromised patients.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Population group: only adults (18 years old or older)
As prophylaxis of deep fungal infections anticipated to be susceptible to itraconazole, when standard therapy is considered inappropriate, in patients with haematological malignancy or undergoing bone marrow transplant, and who are expected to become neutropenic (i.e. <500 cells/µl). At present there are insufficient clinical efficacy data in the prevention of aspergillosis.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Population group: only adults (18 - 65 years old)
Itraconazole is indicated in the following systemic fungal conditions when first-line systemic anti-fungal therapy is inappropriate or has proved ineffective. (This may be due to underlying pathology, insensitivity of the pathogen or drug toxicity).
Treatment of aspergillosis, candidosis and cryptococcosis (including cryptococcal meningitis): in immunocompromised patients with cryptococcosis and in all patients with cryptococcosis of the central nervous system.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Itraconazole is contraindicated in the following cases:
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