Ketoprofen Other names: 2-(3-Benzoylphenyl)propionic acid

Chemical formula: C₁₆H₁₄O₃  Molecular mass: 254.281 g/mol  PubChem compound: 3825

Therapeutic indications

Ketoprofen is indicated for:

Arthritis, musculoskeletal syndromes, dysmenorrhea

Population group: only adults (18 years old or older)

Ketoprofen is recommended in the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute articular and peri-articular disorders, (bursitis, capsulitis, synovitis, tendinitis), cervical spondylitis, low back pain (strain, lumbago, sciatica, fibrositis), painful musculo-skeletal conditions, acute gout, dysmenorrhoea and control of pain and inflammation following orthopaedic surgery.

Ketoprofen reduces joint pain and inflammation and facilitates increase in mobility and functional independence. As with other non-steroidal anti-inflammatory agents, it does not cure the underlying disease.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Irritating and inflammatory conditions of the oral cavity

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Symptomatic relief of irritating and inflammatory conditions of the oral cavity for a short period of time.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Painful musculoskeletal conditions caused by trauma, pain of non serious arthritis

Population group: only adults (18 years old or older)

Relief of acute painful musculoskeletal conditions caused by trauma, such as sports injuries, sprains, strains and contusions.

Pain of non serious arthritis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Ketoprofen is contraindicated in the following cases:

Lactation

Lactation

Pregnancy

Pregnancy

Active peptic ulcer, history of gastrointestinal bleeding

at least one of
Peptic ulcer
History of gastrointestinal bleed
H/O: gastric ulcer
Gastrointestinal perforation

History of hypersensitivity reactions to aspirin or other NSAIDs

at least one of
Aspirin allergy
NSAID-induced anaphylactoid reaction

Haemorrhagic diathesis, severe hepatic insufficiency, severe renal insufficiency

at least one of
Blood coagulation disorder
Hepatic failure stage IV

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe heart failure

Heart failure

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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