Lamotrigine

Chemical formula: C₉H₇Cl₂N₅  Molecular mass: 256.091 g/mol  PubChem compound: 3878

Therapeutic indications

Lamotrigine is indicated for:

Epilepsy

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

  • Adjunctive or monotherapy treatment of partial seizures and generalised seizures, including tonic clonic seizures.
  • Seizures associated with Lennox Gastaut syndrome. Lamotrigine is given as adjunctive therapy but may be the initial antiepileptic drug (AED) to start with in Lennox Gastaut syndrome.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Epilepsy

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old)

  • Adjunctive or monotherapy treatment of partial seizures and generalised seizures, including tonic clonic seizures.
  • Seizures associated with Lennox Gastaut syndrome. Lamotrigine are given as adjunctive therapy but may be the initial antiepileptic drug (AED) to start with in Lennox Gastaut syndrome.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Bipolar I disorder

Population group: only adults (18 years old or older)

Prevention of depressive episodes in patients with bipolar I disorder who experience predominantly depressive episodes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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Summary of Product Characteristics (SPC) 2019: LAMOTRIGINE / MYLAN Dispersible tablets
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