Landiolol

Chemical formula: C₂₅H₃₉N₃O₈  Molecular mass: 509.6 g/mol  PubChem compound: 114905

Therapeutic indications

Landiolol is indicated for:

Supraventricular tachycardia

Population group: only adults (18 years old or older)

Supraventricular tachycardia and for the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short acting agent is desirable.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Sinus tachycardia

Population group: only adults (18 - 65 years old)

Non-compensatory sinus tachycardia where, in the physician’s judgment the rapid heart rate requires specific intervention.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Landiolol is contraindicated in the following cases:

Severe bradycardia

Severe sinus bradycardia

Sick sinus syndrome

Sick sinus syndrome

2nd degree AV block, 3rd degree AV block

at least one of
Second degree atrioventricular block
Complete atrioventricular block

Cardiogenic shock

Cardiogenic shock

Severe hypotension

Hypotension

Decompensated heart failure

Decompensated chronic heart failure

Pulmonary hypertension

Pulmonary hypertension

Non-treated phaeochromocytoma

Phaeochromocytoma

Acute asthmatic attack

Exacerbation of asthma

Severe, uncorrectable metabolic acidosis

Metabolic acidosis

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Summary of Product Characteristics (SPC) : RAPIBLOC Powder for solution for infusion
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