Lansoprazole

Chemical formula: C₁₆H₁₄F₃N₃O₂S  Molecular mass: 369.361 g/mol  PubChem compound: 3883

Active ingredient description

Lansoprazole is a gastric proton pump inhibitor. It inhibits the final stage of gastric acid formation by inhibiting the activity of H+/K+ ATPase of the parietal cells in the stomach. The inhibition is dose-dependent and reversible, and the effect applies to both basal and stimulated secretion of gastric acid.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A02BC03 Lansoprazole A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BC Proton pump inhibitors
Discover more medicines within A02BC03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PREVACID Delayed-release capsule / Delayed-release tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
LANSOPRAZOLE Gastro-resistant capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 103577-45-3
DrugBank Drug: DB00448
KEGG Drug: D00355
PubChem Compound: 3883
RxNorm Ingredient: 17128
SNOMED-CT Concept: 386888004
Lansoprazole (substance)
UNII Identifier: 0K5C5T2QPG
LANSOPRAZOLE

Medicines

Lansoprazole is an active ingredient of these brands:

United States (US)

Australia (AU)

Brazil (BR)

Canada (CA)

Croatia (HR)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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