Chemical formula: C₁₉H₁₈F₃N₃O₂ Molecular mass: 377.367 g/mol PubChem compound: 11610526
Lasmiditan is a high affinity, centrally-penetrant, 5-hydroxytriptamine 1F (5-HT1F) receptor agonist. The precise mechanism of action is unknown, however, the therapeutic effects of lasmiditan in the treatment of migraine presumably involve agonistic effects at the 5-HT1F receptor, a decrease of neuropeptide release and an inhibition of pain pathways, including the trigeminal nerve.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| REYVOW Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| RAYVOW Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Lasmiditan is an active ingredient of these brands:
United States (US)Austria (AT)Croatia (HR)Estonia (EE)France (FR)Ireland (IE)Italy (IT)Japan (JP)Lithuania (LT)Spain (ES)Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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