Lazertinib

Chemical formula: C₃₀H₃₄N₈O₃  Molecular mass: 554.275 g/mol  PubChem compound: 121269225

Active ingredient description

Lazertinib is an irreversible EGFR tyrosine kinase inhibitor (TKI). It selectively inhibits both primary activating EGFR mutations (exon 19 deletions and exon 21 L858R substitution mutations) and the EGFR T790M resistance mutation, while having less activity against wild-type EGFR.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
L01EB09 L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
Discover more medicines within L01EB09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 LAZCLUZE Film-coated tablet MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

DrugBank Drug: DB16216
KEGG Drug: D11980
PubChem Compound: 121269225
RxNorm Ingredient: 2691150
UNII Identifier: 4A2Y23XK11
LAZERTINIB

Medicines

Lazertinib is an active ingredient of these brands:

Austria (AT)

France (FR)

Lithuania (LT)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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