Chemical formula: C₁₇H₂₅NO₃ Molecular mass: 291.385 g/mol PubChem compound: 39468
Levobunolol is a non-cardioselective beta-adrenoceptor blocking agent, equipotent at both beta1 and beta2 receptors. The primary mechanism of action of levobunolol in reducing intraocular pressure is most likely a decrease in aqueous humor production. Levobunolol reduces intraocular pressure with little or no effect on pupil size in contrast to the miosis which cholinergic agents are known to produce.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| S01ED03 | Levobunolol | S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01ED Beta blocking agents |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BETAGAN Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Levobunolol is an active ingredient of these brands:
United States (US)
Austria (AT)
France (FR)
Germany (DE)
Ireland (IE)
New Zealand (NZ)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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