Levocetirizine

Chemical formula: C₂₁H₂₅ClN₂O₃  Molecular mass: 388.89 g/mol  PubChem compound: 1549000

Active ingredient description

Levocetirizine, the ® enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors. Pharmacodynamic studies in healthy volunteers demonstrate that, at half the dose, levocetirizine has comparable activity to cetirizine, both in the skin and in the nose.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AE09 Levocetirizine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AE Piperazine derivatives
Discover more medicines within R06AE09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
XYZAL Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 130018-77-8
DrugBank Drug: DB06282
KEGG Drug: D07402
PubChem Compound: 1549000
RxNorm Ingredient: 356887
SNOMED-CT Concept: 421889003
Levocetirizine (substance)
UNII Identifier: 6U5EA9RT2O
LEVOCETIRIZINE

Medicines

Levocetirizine is an active ingredient of these brands:

United States (US)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Austria (AT)

  • LECISYN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LECIVRIENS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Brazil (BR)

  • RIZI as LEVOCETIRIZINE DIHYDROCHLORIDE
  • VOCETY as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZYXEM as LEVOCETIRIZINE DIHYDROCHLORIDE

  • (combination) LEVOLUKAST as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) RIZI-M as LEVOCETIRIZINE DIHYDROCHLORIDE

Croatia (HR)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

  • ALERG-LETIC as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALERGIPLUS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALERLIV as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ANTISS as LEVOCETIRIZINE HYDROCHLORIDE
  • BERKALER as LEVOCETIRIZINE DIHYDROCHLORIDE
  • DEGRALER as LEVOCETIRIZINE DIHYDROCHLORIDE
  • GLENCET as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVOC as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOFLASH as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOSTAV as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOTREX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOWIN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LIBBERA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LOMAZOL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • NEO-ALERTOP as LEVOCETIRIZINE DIHYDROCHLORIDE
  • RASERLEV
  • RESPIXION PLUS
  • RINOCET as LEVOCETIRIZINE DIHYDROCHLORIDE
  • SINALERGIC as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XUZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZIVAL as LEVOCETIRIZINE DIHYDROCHLORIDE

  • (combination) ANTISS D as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) ANTISS M as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) ASMICHEM DUO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) BERKALER PLUS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) GLEMONT L as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LEVOC NF as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LIBBERA D as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LOMAZOL D as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LUZKA COMPUESTO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) MONTLEVO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) NORAVER DIA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) NORAVER G FAST as LEVOCETIRIZINE DIHYDROCHLORIDE

Estonia (EE)

  • CEZERA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Finland (FI)

  • LEVAZYR as LEVOCETIRIZINE DIHYDROCHLORIDE
  • NOCEDAN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

France (FR)

  • XYZALL as LEVOCETIRIZINE DIHYDROCHLORIDE

Hong Kong (HK)

  • ALCET as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALLERCLEAR as LEVOCETIRIZINE HYDROCHLORIDE
  • CETIZAL as LEVOCETIRIZINE HYDROCHLORIDE
  • ELETIN as LEVOCETIRIZINE HYDROCHLORIDE
  • GLENCET as LEVOCETIRIZINE HYDROCHLORIDE
  • KETRAZIN as LEVOCETIRIZINE HYDROCHLORIDE
  • LEOCET-5 as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVOCERTEC as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVOCEZAL as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVOTIL as LEVOCETIRIZINE HYDROCHLORIDE
  • MINLO as LEVOCETIRIZINE HYDROCHLORIDE
  • SINUSCLEAR as LEVOCETIRIZINE HYDROCHLORIDE
  • XIZYNE as LEVOCETIRIZINE HYDROCHLORIDE
  • XTRAZINE as LEVOCETIRIZINE HYDROCHLORIDE
  • XYLACLEAR as LEVOCETIRIZINE HYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Ireland (IE)

  • MUNTEL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • RINOZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Italy (IT)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Japan (JP)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Lithuania (LT)

  • CEZERA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZALL as LEVOCETIRIZINE DIHYDROCHLORIDE

Malta (MT)

  • RINOZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZALL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZOBRAL

Mexico (MX)

  • XUZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

  • (combination) MISDAPRE RAC as LEVOCETIRIZINE DIHYDROCHLORIDE

Netherlands (NL)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

New Zealand (NZ)

  • ELERHIN as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVOCLEAR as LEVOCETIRIZINE HYDROCHLORIDE
  • LEVRIX as LEVOCETIRIZINE HYDROCHLORIDE
  • SELCET as LEVOCETIRIZINE HYDROCHLORIDE

Nigeria (NG)

  • CALIVIDA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CERIZINE as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CETIDYN-L as LEVOCETIRIZINE DIHYDROCHLORIDE
  • FITIN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • GLENCET as LEVOCETIRIZINE HYDROCHLORIDE
  • HISTOLAT as LEVOCETIRIZINE DIHYDROCHLORIDE
  • RIZCET as LEVOCETIRIZINE DIHYDROCHLORIDE

  • (combination) GLEMONT L as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LEVOMONTE as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) MILTROTIL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) MONTELOVA as LEVOCETIRIZINE DIHYDROCHLORIDE

Poland (PL)

  • AHIST as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALCETYR as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALERGIMED as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CEZERA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CONTRAHIST as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LECETAX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOCEDO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LIRRA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • MEDTAX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • NOSSIN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • VOTREZIN as LEVOCETIRIZINE HYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZENARO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZILOLA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZYX as LEVOCETIRIZINE DIHYDROCHLORIDE

Romania (RO)

  • CEZERA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZENARO as LEVOCETIRIZINE DIHYDROCHLORIDE

Singapore (SG)

  • ALLERZAL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOZINE as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

South Africa (ZA)

  • ALERNOVA as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ALLERWAY 5 as LEVOCETIRIZINE HYDROCHLORIDE
  • CETAWAY as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CETIZAL as LEVOCETIRIZINE HYDROCHLORIDE
  • CETLEV as LEVOCETIRIZINE DIHYDROCHLORIDE
  • CETLOVO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • GLENCET as LEVOCETIRIZINE HYDROCHLORIDE
  • HISCATE as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LECETICIT as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOGEX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVOTRIZ as LEVOCETIRIZINE DIHYDROCHLORIDE
  • TEXAMER as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XENOGEX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Spain (ES)

  • ARALEVO as LEVOCETIRIZINE DIHYDROCHLORIDE
  • MUNTEL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • XAZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Tunisia (TN)

Turkey (TR)

  • ALERINIT as LEVOCETIRIZINE HYDROCHLORIDE
  • CREBROS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVDAY as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVISET as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEVMOL
  • LEVOSETIL as LEVOCETIRIZINE DIHYDROCHLORIDE
  • LEZIN
  • RINIREX as LEVOCETIRIZINE DIHYDROCHLORIDE
  • VIVID as LEVOCETIRIZINE DIHYDROCHLORIDE
  • VOSETRIN as LEVOCETIRIZINE DIHYDROCHLORIDE
  • ZENARO as LEVOCETIRIZINE DIHYDROCHLORIDE

  • (combination) AIRPASS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) ARVAIR as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) BRONCHOREST as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) CETMONT as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) FIXDUAL as LEVOCETIRIZINE HYDROCHLORIDE
  • (combination) LEPIXOS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LEVDAY PLUS as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LEVMONT as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) LEVOKAST as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) MONTAIR as LEVOCETIRIZINE DIHYDROCHLORIDE
  • (combination) NARISAT as LEVOCETIRIZINE DIHYDROCHLORIDE

United Kingdom (UK)

  • XYZAL as LEVOCETIRIZINE DIHYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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