Levomethadone

Chemical formula: C₂₁H₂₇NO  Molecular mass: 309.453 g/mol  PubChem compound: 22267

Active ingredient description

Levomethadone is a fully synthetic opioid analgesic which, as a basic diphenylmethane derivative, can be structurally derived from morphine. Bradycardia, hypotension, bronchoconstriction and antidiuresis are among the pharmacological effects of levomethadone, in addition to other classical opioid effects such as sedation, euphoria and miosis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07BC05 Levomethadone N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BC Drugs used in opioid dependence
Discover more medicines within N07BC05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LEVOMETHADONE Tablets European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 125-58-6
DrugBank Drug: DB13515
KEGG Drug: D08121
PubChem Compound: 22267
RxNorm Ingredient: 236913
UNII Identifier: 6Y75Z4E8NS
LEVOMETHADONE

Medicines

Levomethadone is an active ingredient of these brands:

Austria (AT)

Croatia (HR)

  • LEFISYO as LEVOMETHADONE HYDROCHLORIDE

Estonia (EE)

Finland (FI)

Poland (PL)

Romania (RO)

  • LEFISYO as LEVOMETHADONE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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