Levothyroxine Other names: Synthetic T4 Levothyroxine sodium 3,5,3',5'-tetraiodo-L-thyronine L-thyroxine

Chemical formula: C₁₅H₁₁I₄NO₄  Molecular mass: 776.87 g/mol  PubChem compound: 5819

Active ingredient description

Levothyroxine sodium is used for the treatment of hypothyroidism. The chief action of levothyroxine is to increase the rate of cell metabolism.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H03AA01 Levothyroxine sodium H Systemic hormonal preparations, excl. Sex hormones and insulins → H03 Thyroid therapy → H03A Thyroid preparations → H03AA Thyroid hormones
Discover more medicines within H03AA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LEVOXYL Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
ELTROXIN Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
SYNTHROID Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
LEVOTHYROXINE Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 55-03-8
DrugBank Drug: DB00451
KEGG Drug: D08125
PubChem Compound: 5819
RxNorm Ingredient: 40144
SNOMED-CT Concept: 710809001
Levothyroxine (substance)
UNII Identifier: Q51BO43MG4
LEVOTHYROXINE

Medicines

Levothyroxine is an active ingredient of these brands:

United States (US)

Albania (AL)

  • LETROX as LEVOTHYROXINE SODIUM

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

  • ACCU-THYROX as LEVOTHYROXINE SODIUM
  • EUTHYROX as LEVOTHYROXINE SODIUM
  • T4 as LEVOTHYROXINE SODIUM ANHYDROUS

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

  • ELTROXIN as LEVOTHYROXINE SODIUM
  • EUTHYROX as LEVOTHYROXINE SODIUM
  • T4 as LEVOTHYROXINE SODIUM ANHYDROUS

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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