Chemical formula: C₁₅H₁₈O₃ Molecular mass: 246.302 g/mol PubChem compound: 3965
Loxoprofen has excellent analgesic, anti-inflammatory and antipyretic properties, with particularly potent pain-relieving activity. This drug is a prodrug which is biotransformed into an active metabolite trans-OH form (SRS coordination) to exert its actions. Inhibition of prostaglandin biosynthesis constitutes the mechanism of action of loxoprofen, the site of action being cyclo-oxygenase.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M02AA31 | M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| JAPROLOX Patch | MPI, EU: SmPC |
Loxoprofen is an active ingredient of these brands:
Japan (JP)
Mexico (MX)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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