Chemical formula: C₂₀H₃₂F₂O₅ Molecular mass: 390.468 g/mol PubChem compound: 157920
Lubiprostone is a locally acting chloride channel activator that enhances a chloride-rich intestinal fluid secretion without altering sodium and potassium concentrations in the serum. By increasing intestinal fluid secretion, lubiprostone increases motility in the intestine, thereby facilitating the passage of stool and alleviating symptoms associated with chronic idiopathic constipation (CIC).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A06AX03 | Lubiprostone | A Alimentary tract and metabolism → A06 Laxatives → A06A Laxatives → A06AX Other laxatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| AMITIZA Capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Lubiprostone is an active ingredient of these brands:
United States (US)Brazil (BR)Japan (JP)Singapore (SG)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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