Lynestrenol

Chemical formula: C₂₀H₂₈O  Molecular mass: 284.443 g/mol  PubChem compound: 5857

Pregnancy

This medicine is contraindicated during pregnancy.

Nursing mothers

There are insufficient data on the use of this medicine during breast-feeding to assess potential harm.

Adverse reactions


During continuous treatment regimens with Orgametril, breakthrough bleeding or spotting will occur frequently (over 10%) during the first two months. Later on the frequency gradually decreases.

During cyclic treatment regimens break through bleeding or spotting will be seen occasionally (1-10%).

Temporarily increasing the dose will control the bleeding in most cases.

Other adverse events which occur frequently (over 10%) are: change in Libido (both increase and decrease), nausea or other gastrointestinal disturbances, and weight increase. Adverse events which may be observed occasionally (1-10%) or rare (less than 1%) are: Headache or migrane, dizziness, nervousness, depression, sweating, acne, hirsuitisum, cholasma, rash, pruritus, jaundice, change in lipoprotein profile, alterations in liver function tests , amenonorrohoea, menstrual irregularity , reduced glucose tolerance, breast pain, oedema. Most of these adverse events are transient and of minor importance in many cases.

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Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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