Mangafodipir

Chemical formula: C₂₂H₃₂MnN₄O₁₄P₂+₂  Molecular mass: 691.382 g/mol  PubChem compound: 131704299

Therapeutic indications

Mangafodipir is indicated for:

Magnetic resonance imaging

Population group: only adults (18 years old or older)

Contrast medium for diagnostic Magnetic Resonance Imaging (MRI) for the detection of lesions of the liver suspected to be due to metastatic disease or hepatocellular carcinomas. As an adjunct to MRI to aid in the investigation of focal pancreatic lesions.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Mangafodipir is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Phaeochromocytoma

Phaeochromocytoma

Severely reduced liver function (Child - Pugh class C), severe obstructive hepatobiliary disease

at least one of
Hepatic failure stage IV
Obstruction of biliary tree

Severely reduced renal function

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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