Metformin and Pioglitazone is indicated for:
Population group: only adults (18 years old or older)
Pioglitazone/metformin combination is indicated as second line treatment of type 2 diabetes mellitus adult patients, particularly overweight patients, who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone.
After initiation of therapy with pioglitazone, patients should be reviewed after 3 to 6 months to assess adequacy of response to treatment (e.g. reduction in HbA1c). In patients who fail to show an adequate response, pioglitazone should be discontinued. In light of potential risks with prolonged therapy, prescribers should confirm at subsequent routine reviews that the benefit of pioglitazone is maintained.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Metformin and Pioglitazone is contraindicated in the following cases:
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