Chemical formula: C₁₆H₁₆ClN₃O₃S Molecular mass: 365.835 g/mol PubChem compound: 4170
Metolazone is a diuretic antihypertensive drug for the treatment of edema. Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. The actions of metolazone result from interference with the renal tubular mechanism of electrolyte reabsorption.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03BA08 | Metolazone | C Cardiovascular system → C03 Diuretics → C03B Low-ceiling diuretics, excl. thiazides → C03BA Sulfonamides, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ZAROXOLYN Tablet | Health Products and Food Branch (CA) | MPI, EU: SmPC |
Metolazone is an active ingredient of these brands:
Canada (CA)Estonia (EE)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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