Metoprolol

Chemical formula: C₁₅H₂₅NO₃  Molecular mass: 267.364 g/mol  PubChem compound: 4171

Therapeutic indications

Metoprolol is indicated for:

Hypertension

Population group: only adults (18 years old or older)

Hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Thyrotoxicosis

Population group: only adults (18 years old or older)

Thyrotoxicosis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Angina pectoris

Population group: only adults (18 years old or older)

Angina

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Supraventricular tachycardia

Population group: only adults (18 years old or older)

Supraventricular tachycardia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of migraine

Population group: only adults (18 years old or older)

Preventive procedure and additionally Migraine

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute myocardial infarction

Population group: only adults (18 years old or older)

  • Early intervention of metoprolol tartrate in acute myocardial infarction reduces infarct size and the incidence of ventricular fibrillation. Pain relief may also decrease the need for opiate analgesics.
  • Long-term prophylaxis after recovery from acute myocardial infarction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Metoprolol is contraindicated in the following cases:

Second degree atrioventricular block

Second degree atrioventricular block

Third degree heart block

Complete atrioventricular block

Sick sinus syndrome

Sick sinus syndrome

Prinzmetal angina

Prinzmetal angina

Chronic obstructive pulmonary disease

Chronic obstructive lung disease

Hypotension

Hypotension

Metabolic acidosis

Metabolic acidosis

Phaeochromocytoma

Phaeochromocytoma

Asthma

Airway hyperreactivity

Bronchospasm

Bronchospasm

Diabetes mellitus

Diabetes mellitus

Hypoglycaemia

Hypoglycaemia

Severe peripheral arterial disease

Peripheral arterial occlusive disease

Cardiogenic shock

Cardiogenic shock

Severe heart failure

Heart failure New York Heart Assosiation Class IV

Myocardial infarction complicated by bradycardia, first degree heart block, hypotension, severe heart failure, cardiogenic shock

Myocardial infarction and additionally at least one of
First degree atrioventricular block
Hypotension
Acute heart failure
Cardiogenic shock

Bradycardia (<45-50 bpm)

Bradycardia

Uncontrolled heart failure

Decompensated cardiac failure

Verapamil

Verapamil

Diltiazem

Diltiazem

Disopyramide

Disopyramide

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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