Mexiletine Other names: Mexiletine hydrochloride

Chemical formula: C₁₁H₁₇NO  Molecular mass: 179.259 g/mol  PubChem compound: 4178

Therapeutic indications

Mexiletine is indicated for:

Myotonia in non-dystrophic myotonic disorders

Population group: only adults (18 years old or older)

Mexiletine is indicated for the symptomatic treatment of myotonia in adult patients with non-dystrophic myotonic disorders.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Mexiletine is contraindicated in the following cases:

Ventricular tachyarrhythmia

Ventricular tachyarrhythmia

Medicinal products inducing torsades de pointes

Drugs inducing Torsade de Pointes

Sinus node dysfunction

Coronary sinus rhythm disorder

Atrial tachyarrhythmia, atrial fibrillation, atrial flutter

at least one of
Atrial tachycardia
Atrial fibrillation
Atrial flutter

Heart failure with mid-range (40-49%) and reduced (<40%) ejection fraction

at least one of
Left ventricular ejection fraction decreased
Heart failure with reduced ejection fraction

Symptomatic coronary artery disease

Coronary arteriosclerosis

Myocardial infarction (acute or past), abnormal Q-waves

at least one of
Myocardial infarction
ECG: Q wave abnormal

Heart block

Heart block

Digoxin, lithium, phenytoin, theophylline, warfarin

at least one of
Digoxin
Lithium
Phenytoin
Theophylline
Warfarin

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

Summary of Product Characteristics (SPC) 2019: NAMUSCLA Hard capsule
< Previous: Overview
Next: Precautions >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈