Chemical formula: C₂₂H₃₈O₅ Molecular mass: 382.534 g/mol PubChem compound: 5282381
Misoprostol is an analogue of naturally occurring prostaglandin E1 which promotes peptic ulcer healing and symptomatic relief. Misoprostol protects the gastroduodenal mucosa by inhibiting basal, stimulated and nocturnal acid secretion and by reducing the volume of gastric secretions, the proteolytic activity of the gastric fluid, and increasing bicarbonate and mucus secretion.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A02BB01 | Misoprostol | A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BB Prostaglandins |
| G02AD06 | Misoprostol | G Genito urinary system and sex hormones → G02 Other gynecologicals → G02A Oxytocics → G02AD Prostaglandins |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CYTOTEC Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| MYSODELLE Vaginal delivery system | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TOPOGYNE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Misoprostol is an active ingredient of these brands:
Brazil (BR)Canada (CA)
Croatia (HR)Cyprus (CY)Israel (IL)Nigeria (NG)South Africa (ZA)
Tunisia (TN)
Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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