Mitotane

Chemical formula: C₁₄H₁₀Cl₄  Molecular mass: 320.041 g/mol  PubChem compound: 4211

Therapeutic indications

Mitotane is indicated for:

Adrenal cortical carcinoma (ACC)

Population group: only adults (18 years old or older)

Symptomatic treatment of advanced (unresectable, metastatic or relapsed) adrenal cortical carcinoma (ACC).

The effect of mitotane on non functional adrenal cortical carcinoma is not established.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Adrenal cortical carcinoma (ACC)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Symptomatic treatment of advanced (unresectable, metastatic or relapsed) adrenal cortical carcinoma (ACC).

The effect of mitotane on non functional adrenal cortical carcinoma is not established.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Mitotane is contraindicated in the following cases:

Spironolactone

Spironolactone

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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