Momelotinib

Chemical formula: C₂₃H₂₂N₆O₂  Molecular mass: 414.18 g/mol  PubChem compound: 25062766

Therapeutic indications

Momelotinib is indicated for:

Splenomegaly in primary myelofibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis

Population group: only adults (18 years old or older)

Momelotinib is indicated for the treatment of disease-related splenomegaly or symptoms in adult patients with moderate to severe anaemia who have primary myelofibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis and who are Janus Kinase (JAK) inhibitor naïve or have been treated with ruxolitinib.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Momelotinib is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Active infection

Infectious disease

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