Chemical formula: C₂₁H₂₄FN₃O₄ Molecular mass: 401.431 g/mol PubChem compound: 152946
Moxifloxacin, a fourth-generation fluoroquinolone, has in vitro activity against a wide range of Gram-positive and Gram-negative pathogens. The bactericidal action of moxifloxacin results from the inhibition of both type II topoisomerases (DNA gyrase and topoisomerase IV) required for bacterial DNA replication, transcription and repair.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01MA14 | Moxifloxacin | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones |
| S01AE07 | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MOXIVIG Eye drops | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| AVELOX Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| AVELOX Solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Moxifloxacin is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)
Cyprus (CY)Ecuador (EC)
Estonia (EE)France (FR)
Germany (DE)
Hong Kong (HK)Ireland (IE)
Italy (IT)
Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)
Spain (ES)Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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