Moxonidine

Chemical formula: C₉H₁₂ClN₅O  Molecular mass: 241.677 g/mol  PubChem compound: 4810

Therapeutic indications

Moxonidine is indicated for:

Mild to moderate essential hypertension

Population group: only adults (18 years old or older)

Essential hypertension

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Moxonidine is contraindicated in the following cases:

Severe renal insufficiency (GFR <30 ml/min)

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe hepatic insufficiency

Hepatic failure stage IV

Cardiac insufficiency

Cardiac failure

Unstable angina pectoris

Preinfarction syndrome

Severe coronary heart disease

Coronary arteriosclerosis

Malignant arrhythmia

at least one of
Ventricular fibrillation
Recurrent ventricular tachycardia
Torsades de pointes

Bradycardia (less than 50 beats/minute at rest)

Bradycardia

Sick sinus syndrome

Sick sinus syndrome

Sino-atrial block

Sinoatrial block

Angioneurotic oedema

Angioedema

Second degree atrioventricular block

Second degree atrioventricular block

Complete atrioventricular block

Complete atrioventricular block

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2018: MOXONIDINE Film-coated tablet
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