Chemical formula: C₁₅H₁₆O₂ Molecular mass: 228.286 g/mol PubChem compound: 4409
Nabumetone is a non acidic non steroidal anti-inflammatory agent with weak prostaglandin synthesis properties. Nabumetone undergoes rapid and extensive metabolism in the liver to 6-methoxy-2-naphthylacetic acid (6-MNA), the principal active metabolite which is a potent inhibitor of prostaglandin synthesis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M01AX01 | Nabumetone | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AX Other antiinflammatory and antirheumatic agents, non-steroids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NABUMETONE Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| RELAFEN Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Nabumetone is an active ingredient of these brands:
United States (US)Estonia (EE)France (FR)Germany (DE)Ireland (IE)Japan (JP)Lithuania (LT)Netherlands (NL)Poland (PL)Spain (ES)Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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