Naloxone

Chemical formula: C₁₉H₂₁NO₄  Molecular mass: 327.374 g/mol  PubChem compound: 5284596

Therapeutic indications

Naloxone is indicated for:

Complete or partial reversal of central nervous system caused by opioids

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Complete or partial reversal of CNS and especially respiratory depression, caused by natural or synthetic opioids.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Suspected acute opioid overdose or intoxication

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

at least one of
Overdose of opiate
Opioid intoxication

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Reversal of respiratory and other CNS depression in the neonate whose mothers have received opioids

Population group: only newborns (0 - 40 days old)

Reversal of opiate activity

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Immediate administration as emergency therapy for known or suspected opioid overdose

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Naloxone is intended for immediate administration as emergency therapy for known or suspected opioid overdose as manifested by respiratory and/or central nervous system depression in both non-medical and healthcare settings.

Naloxone is indicated in adults and adolescents aged 14 years and over.

Naloxone is not a substitute for emergency medical care.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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