Chemical formula: C₂₂H₂₅F₂NO₄ Molecular mass: 405.435 g/mol PubChem compound: 71301
Nebivolol is a racemate of two enantiomers, SRRR-nebivolol (or d-nebivolol) and RSSS-nebivolol (or l-nebivolol). It is a competitive and selective beta-receptor antagonist and it has mild vasodilating properties due to an interaction with the L-arginine/nitric oxide pathway.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
C07AB12 | Nebivolol | C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AB Beta blocking agents, selective |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
NEBILET Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
BYSTOLIC Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Nebivolol is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Estonia (EE)Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Italy (IT)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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