Chemical formula: C₁₃H₈Cl₂N₂O₄ Molecular mass: 327.12 g/mol PubChem compound: 4477
Niclosamide acts locally by direct contact with the tapeworm’s scolex. Niclosamide inhibits oxidative phosphorylation in the parasite’s mitochondria, resulting in death of the scolex and adjoining segments. The segment chain then loses its grip and is eliminated from the intestine during bowel movement, either as a whole or in individual small parts.
Niclosamide is poorly absorbed.
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