Nilotinib

Chemical formula: C₂₈H₂₂F₃N₇O  Molecular mass: 529.516 g/mol  PubChem compound: 644241

Therapeutic indications

Nilotinib is indicated for:

Philadelphia chromosome positive chronic myelogenous leukaemia (CML)

Population group: only adults (18 years old or older)

Nilotinib is indicated for the treatment of:

  • adult and paediatric patients with newly diagnosed Philadelphia chromosome positive chronic myelogenous leukaemia (CML) in the chronic phase,
  • adult patients with chronic phase and accelerated phase Philadelphia chromosome positive CML with resistance or intolerance to prior therapy including imatinib. Efficacy data in patients with CML in blast crisis are not available,
  • paediatric patients with chronic phase Philadelphia chromosome positive CML with resistance or intolerance to prior therapy including imatinib.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Philadelphia chromosome positive chronic myelogenous leukaemia (CML)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Nilotinib is indicated for the treatment of:

  • adult and paediatric patients with newly diagnosed Philadelphia chromosome positive chronic myelogenous leukaemia (CML) in the chronic phase,
  • adult patients with chronic phase and accelerated phase Philadelphia chromosome positive CML with resistance or intolerance to prior therapy including imatinib. Efficacy data in patients with CML in blast crisis are not available,
  • paediatric patients with chronic phase Philadelphia chromosome positive CML with resistance or intolerance to prior therapy including imatinib.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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