Chemical formula: C₁₉H₁₉N₃O₆ Molecular mass: 385.371 g/mol PubChem compound: 4494
Nilvadipine at very low concentrations inhibits the influx of calcium into the cell of the smooth vascular musculature and thereby cause vasodilatation. The myogenic vascular-wall tonus is reduced and the peripheral vascular resistance diminished. This in turn results in an antihypertensive effect.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C08CA10 | Nilvadipine | C Cardiovascular system → C08 Calcium channel blockers → C08C Selective calcium channel blockers with mainly vascular effects → C08CA Dihydropyridine derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NIVADIL Prolonged release capsule, hard | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
Nilvadipine is an active ingredient of these brands:
Austria (AT)Finland (FI)Japan (JP)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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