Nintedanib

Chemical formula: C₃₁H₃₃N₅O₄  Molecular mass: 539.625 g/mol  PubChem compound: 9809715

Therapeutic indications

Nintedanib is indicated for:

Idiopathic pulmonary fibrosis

Population group: only adults (18 years old or older)

Nintedanib is indicated in adults for the treatment of idiopathic pulmonary fibrosis (IPF).

Nintedanib is also indicated in adults for the treatment of other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-small cell lung cancer adenocarcinoma (2nd line treatment)

Population group: only adults (18 years old or older)

Nintedanib is indicated in combination with docetaxel for the treatment of adult patients with locally advanced, metastatic or locally recurrent non-small cell lung cancer (NSCLC) of adenocarcinoma tumour histology after first-line chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Systemic sclerosis associated interstitial lung disease

Population group: only adults (18 years old or older)

Nintedanib is indicated in adults for the treatment of systemic sclerosis associated interstitial lung disease (SSc-ILD).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Nintedanib is contraindicated in the following cases:

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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