Chemical formula: C₁₉H₂₀N₄O Molecular mass: 320.396 g/mol PubChem compound: 24958200
Niraparib is an inhibitor of poly(ADP-ribose) polymerase (PARP) enzymes, PARP-1 and PARP-2, which play a role in DNA repair.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01XK02 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ZEJULA Hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Niraparib is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)Estonia (EE)Finland (FI)Hong Kong (HK)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Netherlands (NL)New Zealand (NZ)Poland (PL)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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