Nitric oxide (NO)

Chemical formula: NO  Molecular mass: 30.006 g/mol  PubChem compound: 145068

Active ingredient description

Nitric oxide is a compound produced by many cells of the body. It relaxes vascular smooth muscle by binding to the haeme moiety of cytosolic guanylate cyclase. When inhaled, nitric oxide produces selective pulmonary vasodilation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R07AX01 Nitric oxide R Respiratory system → R07 Other respiratory system products → R07A Other respiratory system products → R07AX Other respiratory system products
Discover more medicines within R07AX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NOXIVENT 101 Inhalation gas FDA, National Drug Code (US) MPI, US: SPL/PLR
INOMAX Inhalation gas European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 10102-43-9
DrugBank Drug: DB00435
KEGG Drug: D00074
PubChem Compound: 145068
RxNorm Ingredient: 7442
SNOMED-CT Concept: 6710000
Nitric oxide (substance)
UNII Identifier: 31C4KY9ESH
NITRIC OXIDE

Medicines

Nitric oxide (NO) is an active ingredient of these brands:

United States (US)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Poland (PL)

Romania (RO)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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