Chemical formula: C₈H₆N₄O₅ Molecular mass: 238.159 g/mol PubChem compound: 6604200
Nitrofurantoin is a broad spectrum antibacterial agent, active against the majority of urinary pathogens. It is bactericidal in renal tissue and throughout the urinary tract. The wide range of organisms sensitive to the bacterial activity include Escherichia coli, Enteroccus faecalis, Klebsiella species, Enterobacter species, Staphylococcus species: (e.g. S. aureus, S. saprophyticus, S. epidermidis).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01XE01 | Nitrofurantoin | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XE Nitrofuran derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MACROBID Prolonged-release capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| NITROFURANTOIN Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Nitrofurantoin is an active ingredient of these brands:
United States (US)Australia (AU)Austria (AT)Brazil (BR)Canada (CA)Cyprus (CY)Ecuador (EC)Estonia (EE)Finland (FI)
France (FR)Germany (DE)
Ireland (IE)Israel (IL)Italy (IT)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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