Obinutuzumab

Chemical formula: C₆₅₁₂H₁₀₀₆₀N₁₇₁₂O₂₀₂₀S₄₄ 

Therapeutic indications

Obinutuzumab is indicated for:

Chronic lymphocytic leukaemia (CLL)

Population group: only adults (18 years old or older)

Obinutuzumab in combination with chlorambucil is indicated for the treatment of adult patients with previously untreated chronic lymphocytic leukaemia (CLL) and with comorbidities making them unsuitable for full-dose fludarabine based therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Follicular lymphoma (FL)

Population group: only adults (18 years old or older)

Obinutuzumab in combination with chemotherapy, followed by obinutuzumab maintenance therapy in patients achieving a response, is indicated for the treatment of patients with previously untreated advanced follicular lymphoma (FL).

Obinutuzumab in combination with bendamustine followed by obinutuzumab maintenance is indicated for the treatment of patients with follicular lymphoma (FL) who did not respond or who progressed during or up to 6 months after treatment with rituximab or a rituximab-containing regimen.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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