Chemical formula: C₁₈H₂₀FN₃O₄ Molecular mass: 361.368 g/mol PubChem compound: 4583
Ofloxacin is a quinolone-carboxylic acid derivative with a wide range of antibacterial activity against both Gram-negative and Gram-positive organisms. The primary mode of action of the quinolones is the specific inhibition of bacterial DNA gyrase. This enzyme is required for DNA replication, transcription, repair and recombination.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01MA01 | Ofloxacin | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones |
| S01AE01 | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones | |
| S02AA16 | S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EXOCIN Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TARIVID Solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| OFLOXACIN Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| OCUFLOX Ophthalmic solution | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Ofloxacin is an active ingredient of these brands:
United States (US)Australia (AU)Canada (CA)Cyprus (CY)Estonia (EE)Finland (FI)France (FR)Hong Kong (HK)Israel (IL)Japan (JP)Malta (MT)Nigeria (NG)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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