Opicapone

Chemical formula: C₁₅H₁₀Cl₂N₄O₆  Molecular mass: 413.17 g/mol 

Therapeutic indications

Opicapone is indicated for:

Parkinson's disease

Population group: only adults (18 years old or older)

Opicapone is indicated as adjunctive therapy to preparations of levodopa/DOPA decarboxylase inhibitors (DDCI) in adult patients with Parkinson’s disease and end-of-dose motor fluctuations who cannot be stabilised on those combinations.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Opicapone is contraindicated in the following cases:

Phaeochromocytoma, paraganglioma, other catecholamine secreting neoplasms

at least one of
Phaeochromocytoma
Paraganglioma

History of neuroleptic malignant syndrome, history of non-traumatic rhabdomyolysis

at least one of
Neuroleptic malignant syndrome
Non-traumatic rhabdomyolysis

Monoamine oxidase (MAO-A and MAO-B) inhibitors

at least one of
Selective Monoamine Oxidase Inhibitors A
Selective Monoamine Oxidase Inhibitors B

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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