Opium

Therapeutic indications

Opium is indicated for:

Diarrhoea

Population group: only adults (18 - 65 years old)

Opium alkaloids is indicated for severe diarrhoea such as diarrhoea caused by cytostatic medication, radiation or neuroendocrine tumours when use of other anti-diarrhoea treatments have not given sufficient effect.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

500-1500 mg in 2-3 divided doses daily

Contraindications

Opium is contraindicated in the following cases:

Opiate dependency

Opium dependence

Glaucoma

Severe hepatic impairment

Hepatic failure stage IV

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Delirium tremens

Alcohol withdrawal delirium

Severe head trauma

Major head injury

Paralytic ileus

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