Ospemifene

Chemical formula: C₂₄H₂₃ClO₂  Molecular mass: 378.891 g/mol  PubChem compound: 3036505

Therapeutic indications

Ospemifene is indicated for:

Moderate to severe symptomatic vulvar and vaginal atrophy (VVA) in post-menopausal women

Population group: women, only adults (18 years old or older)

Senile atrophic vaginitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Ospemifene is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Fertility

Fertility

History of venous thromboembolic events (VTEs)

at least one of
History of venous thromboembolic disease
History of deep vein thrombosis
Pulmonary embolism
Thrombosis of retinal vein

Unexplained vaginal bleeding

Observations of vaginal bleeding

Breast cancer

at least one of
Malignant tumor of breast
† At risk of breast cancer

Sex-hormone dependent malignancy

Hormone-sensitive cancer

Endometrial hyperplasia

Endometrial hyperplasia

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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