Oxaliplatin Other names: Oxaloplatine

Chemical formula: C₈H₁₂N₂O₄Pt  Molecular mass: 397.294 g/mol  PubChem compound: 6857599

Therapeutic indications

Oxaliplatin is indicated for:

Colorectal cancer

Population group: only adults (18 years old or older)

Oxaliplatin in combination with 5-fluorouracil (5-FU) and folinic acid (FA) is indicated for:

  • Adjuvant treatment of stage III (Duke’s C) colon cancer after complete resection of primary tumor.
  • Treatment of metastatic colorectal cancer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Oxaliplatin is contraindicated in the following cases:

Lactation

Lactation

Severely impaired renal function (creatinine clearance <30 ml/min)

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Myelosuppression

Myelosuppression

Peripheral sensory neuropathy

Peripheral sensory neuropathy

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Summary of Product Characteristics (SPC) 2019: OXALIPLATIN Concentrate for solution
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