Chemical formula: C₄₇H₅₁NO₁₄ Molecular mass: 853.906 g/mol PubChem compound: 36314
Paclitaxel is an antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilises microtubules by preventing depolymerisation. This stability results in the inhibition of the normal dynamic reorganisation of the microtubule network that is essential for vital interphase and mitotic cellular functions.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01CD01 | Paclitaxel | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products → L01CD Taxanes |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ABRAXANE Powder for suspension for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
Paclitaxel is an active ingredient of these brands:
United States (US)
Australia (AU)
Brazil (BR)Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)Estonia (EE)
France (FR)
Italy (IT)Japan (JP)Lithuania (LT)
New Zealand (NZ)
Singapore (SG)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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