Parecoxib

Chemical formula: C₁₉H₁₈N₂O₄S  Molecular mass: 370.422 g/mol  PubChem compound: 119828

Therapeutic indications

Parecoxib is indicated for:

Postoperative pain

Population group: only adults (18 years old or older)

For the short-term treatment of postoperative pain in adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Parecoxib is contraindicated in the following cases:

Severe hepatic impairment

Hepatic failure stage IV

Pregnancy

Pregnancy

Lactation

Lactation

Active peptic ulceration, gastrointestinal (GI) bleeding

at least one of
Peptic ulcer
Gastrointestinal hemorrhage

Allergic-type reactions to acetylsalicylic acid or nonsteroidal anti-inflammatory drugs (NSAIDs)

at least one of
Aspirin allergy
NSAID-induced anaphylactoid reaction

Inflammatory bowel disease

Inflammatory bowel disease

Congestive heart failure (NYHA II-IV)

Congestive heart failure

Treatment of post-operative pain following coronary artery bypass graft (CABG) surgery

Postoperative pain and additionally Coronary artery bypass graft

Ischaemic heart disease, peripheral arterial disease, cerebrovascular disease

at least one of
Ischemic heart disease
Peripheral arterial vascular disease
Cerebrovascular disease

History of serious allergic drug reaction, known hypersensitivity to sulfonamides

at least one of
Drug allergy
Sulfonamide adverse reaction

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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