Paromomycin

Molecular mass: 615.629 g/mol  PubChem compound: 165580

Active ingredient description

Paromomycin is an aminoglycoside antibiotic derived from Streptomyces rimosus var paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A07AA06 Paromomycin A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07A Intestinal antiinfectives → A07AA Antibiotics
Discover more medicines within A07AA06

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 7542-37-2
DrugBank Drug: DB01421
PubChem Compound: 165580
RxNorm Ingredient: 7934
SNOMED-CT Concept: 34375008
Paromomycin (substance)
SNOMED-CT Concept: 38044001
Paromomycin (substance)
UNII Identifier: 61JJC8N5ZK
PAROMOMYCIN

Medicines

Paromomycin is an active ingredient of these brands:

Austria (AT)

Canada (CA)

Estonia (EE)

Israel (IL)

  • (combination) LESHCUTAN as PAROMOMYCIN SULFATE

Italy (IT)

  • HUMATIN as PAROMOMYCIN SULFATE
  • KAMAN as PAROMOMYCIN SULFATE

Japan (JP)

Malta (MT)

South Africa (ZA)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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