Chemical formula: C₅₈H₆₆N₁₀O₉ Molecular mass: 1,047.206 g/mol PubChem compound: 9941444
Pasireotide is a novel cyclohexapeptide, injectable somatostatin analogue. Pasireotide exerts its pharmacological activity via binding to somatostatin receptors. Somatostatin receptors are expressed in many tissues, especially in neuroendocrine tumours in which hormones are excessively secreted, including ACTH in Cushing’s disease.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| H01CB05 | Pasireotide | H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01C Hypothalamic hormones → H01CB Somatostatin and analogues |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SIGNIFOR Powder and solvent for suspension for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
| SIGNIFOR Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC |
Pasireotide is an active ingredient of these brands:
United States (US)Australia (AU)
Austria (AT)Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)Finland (FI)France (FR)Hong Kong (HK)
Ireland (IE)Israel (IL)
Italy (IT)Japan (JP)
Lithuania (LT)Netherlands (NL)New Zealand (NZ)
Poland (PL)Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
