Pegfilgrastim

Active ingredient description

Pegfilgrastim is a sustained duration form of filgrastim due to decreased renal clearance. Pegfilgrastim and filgrastim have been shown to have identical modes of action, causing a marked increase in peripheral blood neutrophil counts within 24 hours, with minor increases in monocytes and/or lymphocytes.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L03AA13 Pegfilgrastim L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AA Colony stimulating factors
Discover more medicines within L03AA13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
FULPHILA Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 208265-92-3
DrugBank Drug: DB00019
KEGG Drug: D06889
RxNorm Ingredient: 338036
SNOMED-CT Concept: 385544005
Pegfilgrastim (substance)
UNII Identifier: 3A58010674
PEGFILGRASTIM

Medicines

Pegfilgrastim is an active ingredient of these brands:

United States (US)

Brazil (BR)

Cyprus (CY)

Hong Kong (HK)

Japan (JP)

Netherlands (NL)

New Zealand (NZ)

Singapore (SG)

South Africa (ZA)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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