Pegvisomant is an analogue of human growth hormone that has been genetically modified to be a growth hormone receptor antagonist for the treatment of adult patients with acromegaly. Pegvisomant is highly selective for the GH receptor, and does not cross-react with other cytokine receptors, including prolactin.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
H01AX01 | Pegvisomant | H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01A Anterior pituitary lobe hormones and analogues → H01AX Other anterior pituitary lobe hormones and analogues |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
SOMAVERT Powder and solvent for solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC |
Pegvisomant is an active ingredient of these brands:
Australia (AU)Austria (AT)Brazil (BR)Canada (CA)Croatia (HR)Estonia (EE)Finland (FI)France (FR)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)Netherlands (NL)Poland (PL)Romania (RO)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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