Chemical formula: C₃₇H₄₉N₇O₉S Molecular mass: 767.9 g/mol PubChem compound: 9853654
Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test. Pentagastrin binds to the cholecystokinin-B receptor, which is expressed widely in the brain. Activation of these receptors activates the phospholipase C second messenger system. When given intravenously it may cause panic attacks.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V04CG04 | Pentagastrin | V Various → V04 Diagnostic agents → V04C Other diagnostic agents → V04CG Tests for gastric secretion |
Pentagastrin is an active ingredient of these brands:
Estonia (EE)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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