Phenobarbital Other names: Phenobarbitone

Chemical formula: C₁₂H₁₂N₂O₃  Molecular mass: 232.235 g/mol  PubChem compound: 4763

Therapeutic indications

Phenobarbital is indicated for:

Epilepsy

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

An anti-convulsant for the treatment all forms of epilepsy except absence seizures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Epilepsy

Population group: only adults (18 years old or older)

The treatment and control of all forms of epilepsy, except absence seizures. Phenobarbital should only be used in the treatment of febrile convulsions in exceptional circumstances.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Phenobarbital is contraindicated in the following cases:

Hypersensitivity to phenobarbital

Phenobarbitone allergy

Severe respiratory depression

Decreased respiratory function

Acute intermittent porphyria

Acute intermittent porphyria

Severe impairment of hepatic function

Hepatic failure stage IV

Severe impairment of renal function

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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