Pilocarpine

Chemical formula: C₁₁H₁₆N₂O₂  Molecular mass: 208.257 g/mol  PubChem compound: 5910

Active ingredient description

Pilocarpine is a cholinergic parasympathomimetic agent exerting a broad spectrum of pharmacologic effects with predominant muscarinic action. Pilocarpine, in appropriate dosage, can increase secretion by exocrine glands such as the sweat, salivary, lacrimal, gastric, pancreatic and intestinal glands and the mucous cells of the respiratory tract.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07AX01 Pilocarpine N Nervous system → N07 Other nervous system drugs → N07A Parasympathomimetics → N07AX Other parasympathomimetics
Discover more medicines within N07AX01
S01EB01 Pilocarpine S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EB Parasympathomimetics
Discover more medicines within S01EB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SALAGEN Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PILOCARPINE Eye drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 54-71-7
DrugBank Drug: DB01085
KEGG Drug: D00525
PubChem Compound: 5910
RxNorm Ingredient: 8328
SNOMED-CT Concept: 372895002
Pilocarpine (substance)
UNII Identifier: 01MI4Q9DI3
PILOCARPINE

Medicines

Pilocarpine is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE

Brazil (BR)

  • PILOCAN as PILOCARPINE HYDROCHLORIDE
  • PILOSOL as PILOCARPINE HYDROCHLORIDE

Canada (CA)

Cyprus (CY)

Estonia (EE)

Finland (FI)

  • ISOPTO-CARPINE as PILOCARPINE HYDROCHLORIDE
  • SALAGEN as PILOCARPINE HYDROCHLORIDE

  • (combination) FOTIL as PILOCARPINE HYDROCHLORIDE

France (FR)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE

Germany (DE)

Hong Kong (HK)

Israel (IL)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE
  • SALVAKAL as PILOCARPINE HYDROCHLORIDE

Japan (JP)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE
  • SANPILO as PILOCARPINE HYDROCHLORIDE

Lithuania (LT)

  • (combination) FOTIL as PILOCARPINE HYDROCHLORIDE

Malta (MT)

Netherlands (NL)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE

New Zealand (NZ)

Singapore (SG)

Spain (ES)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE

Tunisia (TN)

  • (combination) CARPILO as PILOCARPINE HYDROCHLORIDE

Turkey (TR)

United Kingdom (UK)

  • SALAGEN as PILOCARPINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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