Pitavastatin

Chemical formula: C₂₅H₂₄FNO₄  Molecular mass: 421.461 g/mol  PubChem compound: 5282452

Active ingredient description

Pitavastatin competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in the biosynthesis of cholesterol, and inhibits cholesterol synthesis in the liver.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C10AA08 Pitavastatin C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AA HMG CoA reductase inhibitors
Discover more medicines within C10AA08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LIVAZO Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
LIVALO Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 147511-69-1
DrugBank Drug: DB08860
KEGG Drug: D01862
PubChem Compound: 5282452
RxNorm Ingredient: 861634
SNOMED-CT Concept: 443586000
Pitavastatin (substance)
UNII Identifier: M5681Q5F9P
PITAVASTATIN

Medicines

Pitavastatin is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

  • EBATZ as PITAVASTATIN CALCIUM
  • LESTER as PITAVASTATIN CALCIUM
  • LIVALO as PITAVASTATIN CALCIUM
  • PIVAST as PITAVASTATIN CALCIUM

France (FR)

Germany (DE)

  • LIVAZO as PITAVASTATIN CALCIUM

Ireland (IE)

  • LIVAZO as PITAVASTATIN CALCIUM

Japan (JP)

  • LIVALO as PITAVASTATIN CALCIUM

  • (combination) LIVAZEBE as PITAVASTATIN CALCIUM PENTAHYDRATE

Malta (MT)

Mexico (MX)

Poland (PL)

Singapore (SG)

  • LIVALO as PITAVASTATIN CALCIUM

Spain (ES)

  • ALIPZA as PITAVASTATIN CALCIUM
  • LIVAZO as PITAVASTATIN CALCIUM

Turkey (TR)

  • ALIPZA as PITAVASTATIN CALCIUM
  • PITAMIN as PITAVASTATIN CALCIUM
  • PITAS as PITAVASTATIN CALCIUM
  • PRATIN as PITAVASTATIN CALCIUM

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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